CORPORATION
Heart Muscle Tissue Regeneration
Experience a revolutionary approach to cardiac care with AIMER at Meridius Bio. Our nanotherapeutic platform is designed for post-myocardial infarction recovery, actively promoting the regeneration of damaged heart muscle tissue. AIMER not only minimizes scarring but sets the stage for improved cardiac function. Backed by scientific validation, it represents a commitment to reshaping the recovery journey after cardiac events. Explore the future of cardiac wellness with AIMER at Meridius Bio. Welcome to a new era in heart muscle tissue regeneration.
Research backed Insight
Myocardial infarction results in significant loss of cardiomyocytes. Intramyocardial injection of 50 μg α-Gal NPs (20 nm diameter) in a rodent model of heart failure promoted macrophage infiltration (4-fold) and subsequent differentiation into functional cardiomyocytes, as evidenced by cardiac-specific gene expression and contractility measurements. Additionally, α-Gal NPs stimulated angiogenesis (increased CD31+ endothelial cells) and improved cardiac function (ejection fraction increased by 15%), providing evidence for their potential in cardiac regenerative therapy.